Dengue: a silent killer’s journey
Dengue is a viral contamination which is going via three levels of transformation wherein it dissipates itself wherein the man or woman goes lower back to his exact health. Each of those 3 stages is marked with the aid of clinical and lab research oriented changes, that facilitates the clinical personnel to discover the diploma of attention required in dealing with the patients.
I. Febrile section
This is the duration wherein the affected person has fever. That is the segment wherein the patients are most involved about. This period can also ultimate about three to 6 days. The period of the febrile segment is dependent on the kind of dengue virus and the immunity of the patient.
Most assume that the fever is the most dangerous part of the illness, but it isn’t.
When the virus enters the body and interacts with the blood, pyrogens are advanced which reasons fever. This period, itself is not harmful and in some this period may quit with convalescence whereas others will input the essential segment.
This period is marked by a drop within the platelet counts with a discount in the total white mobile matter. The discount within the platelets is huge but no longer drastic.
Ii. Important section
This section includes the most dangerous a part of the illness. By this time, the fever has settled and people suppose that they may be out of the woods, and that it’s miles safe to maintain with their day to day sports.
By using this time there’s a rapid drop in the platelet remember inside the full blood depend. That is because of the antibodies ( some due to antibodies of a previous dengue infection)and different immune mediated reactions which reason destruction of the platelets.But the discount of platelets itself isn’t always the worst of it. It’s far the leakage of fluids from the small vessels into the encircling tissues. This is once more because of the immune mediated reactions of the body.If you think of the blood like a lubricant fluid which maintains the clean characteristic of a car, this lubricant fluid incorporates two components; the watery component (plasma of the blood) and a debris factor (cells and platelets). When the tubing of the vehicle is not resilient enough and in growing small pores, in turn ends in extravasation of the liquid out of the tubing (vessels) in to the encircling components. So in effect this ends in thickening of the lubricant fluid.